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Statistic of ATDB |
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Toxin Number : |
3844 |
Species : |
441 |
TO Annotations :
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11626 |
Version : |
1.5 |
Last Update : |
2008-08-13 |
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ATDB version 1.5 release (2008.8.13) |
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609 new toxin sequences and related annotations have been imported into ATDB. The toxin pdb file now can be showed in our website. And a new page named "High Light" was opened to highlight the breakthroughs of toxin research. |
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Publication (2007.10.15) |
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The paper about ATDB database has been accepted by Nucleic Acid Research and will be published on the 2008 Database issue. It now can be downloaded from here. |
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Welcome to Animal Toxin Database (ATDB)
Toxins are, according to Oxford Dictionary of Biochemistry and Molecular Biology, any of various specific posisonous substances that are formed biologically. Conventionally, we also term any molecules from various animal venom as toxin, though it may be not poisonous necessarily.
ATDB, a uni-database platform, was designed to store chemical structures and annotation data of all animal toxins and presents a new terms system (Toxin Ontology) to standardize functional annotations of toxins. The database focuses on answering four basic questions about animal toxins:
What is the category of the toxin(s)? (e.g. Neurotoxin, cytotoxin or others).
What is the biological activity of the toxin(s)? (e.g. Vesicle transport regulation or channel inhibition).
What are the symptoms induced by the toxins(s)? (e.g. Hemolysis, Hemorrhage or Death).
What is the target of the toxin(s)? (e.g. Muscle, Nervous systems or Blood)
ATDB may be the most comprehensive toxin database and now deposits 3235 peptide toxins from 379 species. Most of them are annotated manually using more than 9166 TO terms by trained biologists.
The cite information about ATDB is as follow: Quan-Yuan He, Quan-Ze He, Xing-Can Deng, Lei Yao, Er Meng, Zhong-Hua Liu, and Song-Ping Liang (2007) ATDB : a uni- database platform for animal toxins Nucleic Acids Res., In press; doi: doi:10.1093/nar/gkm832
If you encounter any problem or have any suggestions, please don't hesitate to contact us via Submission page or the email (hqyone@hotmail.com or liangsp@hunnu.edu.cn).
College of Life Sciences
Hunan Normal University
ChangSha, South LuShan road 14#
2007-9-13 |